2016 - 2020
Doktora
SAĞLIK BİLİMLERİ ENSTİTÜSÜ/HİSTOLOJİ VE EMBRİYOLOJİ (DR)/
2014 - 2016
Yüksek Lisans-Tezli
SAĞLIK BİLİMLERİ ENSTİTÜSÜ/HİSTOLOJİ VE EMBRİYOLOJİ (YL) (TEZLİ)/
Tez adı: 17β-östradiol ve 1,25-dihydroksi vitamin D3 uygulanan düz kas hücrelerinde çoğalma ve apoptoz dinamiklerinin epigenetik analizi (2016) Tez Danışmanı: ŞAKİR NECAT YILMAZ
2007 - 2013
Lisans
FEN-EDEBİYAT FAKÜLTESİ/BİYOLOJİK BİLİMLER BÖLÜMÜ/BİYOLOJİ PR. (İNGİLİZCE)/
2017 -
ARAŞTIRMA GÖREVLİSİ
MERSİN ÜNİVERSİTESİ/SAĞLIK BİLİMLERİ ENSTİTÜSÜ/
A. Uluslararası hakemli dergilerde yayımlanan makaleler (20)
Söğüt, F., Uzun, C., Kibar, D., & Çömelekoğlu, Ü. (2024). Investigation of the role of KATP channels in the cytotoxic effect of cypermethrin on rat-derived aortic smooth muscle cells. In DRUG AND CHEMICAL TOXICOLOGY (Vol. 47, Issue 6, pp. 1–8).
Demirbağ, B., Ballı, E., Yıldırım, M., Ünver, H., Temel, G., Yılmaz, M. K., Yıldırım, M., Değirmenci, E., & Kibar, D. (2024). Investigation of the anticancer of photodynamic therapy effects by using the novel Schiff base ligand palladium complexes on human breast cancer cell line. In CHEMICAL PAPERS (Vol. 78, Issue 13, pp. 7611–7621).
Söğüt, F., Akıllı, M., Kaynar, A. H., Tuncel, H., Kibar, D., Yılmaz, Ş. N., & Çömelekoğlu, Ü. (2023). Determination of the effect of silica nanoparticles on TRP currents in retinal pigment epithelial cells by entropy measurement. In MEDICAL HYPOTHESES (Vol. 175, pp. 111081-).
Kaynar, A. H., Kaynar, A. H., Kaynar, H. A., Kaynar, A. H., Çömelekoğlu, Ü., Kibar, D., Yıldırım, M., Yıldırımcan, S., Yılmaz, Ş. N., & Erat, S. (2023). Cytotoxic effect of silica nanoparticles on human retinal pigment epithelial cells. In BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (Vol. 674, pp. 53–61).
Mohsenzadeh, E., Khenoussi, N., Bölgen, N., Kibar, D., Yılmaz, Ş. N., Adolphe, D., & Schacher, L. (2022). Study and development of electrospun (TPU, PA-6)/silicone bilayer membranes for congenital diaphragmatic hernia repair. In POLYMER BULLETIN (Vol. 80, Issue 9, pp. 10309–10333).
Reşitoğlu, M. T., Yılmaz, Ş. N., Güden, D. S., Şenol, Ş. P., Vezir, Ö., Sucu, N., Kibar, D., Tunçtan, B., Fırat, S. Ş., Malık, K. U., Malık, K. U., & Malik, K. (2022). Pharmacological Inhibition of Mammalian Target of Rapamycin Attenuates Deoxycorticosterone Acetate Salt-Induced Hypertension and Related Pathophysiology: Regulation of Oxidative Stress, Inflammation, and Cardiovascular Hypertrophy in Male Rats. In JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (Vol. 79, Issue 3, pp. 355–367).
Şahinoğulları, Z. U., Kara, S. G., Canacankatan, N., Yalaza, C., Kibar, D., & Bayrak, G. (2021). Naringenin Reduces Hepatic Inflammation and Apoptosis Induced by Vancomycin in Rats. In CLINICAL AND EXPERIMENTAL HEALTH SCIENCES (Vol. 11, Issue 2, pp. 191–198).
Güden, D. S., Reşitoğlu, M. T., Şenol, Ş. P., Kibar, D., Yılmaz, Ş. N., Tunçtan, B., Malık, K. U., Malik, K., Malik, K., & Fırat, S. Ş. (2021). mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats. In CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (Vol. 99, Issue 9, pp. 921–934).
Aktaş, S., Demirbağ, B., Çömelekoğlu, Ü., Kibar, D., Uzun, C., Özdemir, E., Yıldırım, M., Özdemir, E., Engiz, B. K., Söğüt, F., Akar, A., Yalın, S., Akar, A. K., & Akar, A. (2019). Ameliorative effects of paricalcitol against 1800-MHz mobile phone radiation-induced skin damage in rats. In Toxicological & Environmental Chemistry (Vol. 101, Issues 9–10, pp. 508–525).
Guzel, S., Güzel, S., Uçkun, Z., Şahinoğulları, Z. U., Canacankatan, N., Antmen, Ş. E., Kibar, D., & Yılmaz, B. C. (2019). Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats. In DRUG AND CHEMICAL TOXICOLOGY (Vol. 43, Issue 6, pp. 630–636).
Güzel, S., Guzel, S., Uçkun, Z., Şahinoğulları, Z. U., Canacankatan, N., Antmen, Ş. E., Kibar, D., & Bayrak, G. (2019). The ameliorating effect of silymarin against vancomycininduced apoptosis and inflammation in rat liver. In Journal of research in pharmacy (online) (Vol. 23, Issue 4, pp. 719–728).
Güden, D. S., Reşitoğlu, M. T., Şenol, Ş. P., Kibar, D., Yılmaz, Ş. N., Tunçtan, B., & Fırat, S. Ş. (2019). mTOR contributes to LPS-triggered neuroinflammation: Modulation of I kappa B-alpha/NF-kappa B/HIF-1 alpha signaling pathway. In German Pharm-Tox Summit 2019 (21st Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 21ts Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) (Vol. 392, Issue S1, pp. 1–88).
Poyraz, S., Canacankatan, N., Belveren, S., Yetkin, D., Kibar, K., Kibar, D., Ülger, M., Sansano, J. M., Özçelik, N., Özçelik, N. D., Yılmaz, Ş. N., & Döndaş, H. A. (2018). Study of the anti(myco)bacterial and antitumor activities of prolinate and N-amidocarbothiolprolinate derivatives based on fused tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione, bearing an indole ring. In Monatshefte für Chemie - Chemical Monthly (Vol. 149, Issue 12, pp. 2253–2263).
Canacankatan, N., Dinç, E., Kibar, D., Yalaza, C., Antmen, Ş. E., Gürler, H. M., Yılmaz, B. C., & Taşdelen, B. (2018). Effect of axitinib on inflammation in experimental corneal neovascularization model in rats. In Cukurova Medical Journal (Vol. 43, Issue Ek 1, pp. 275–284).
Uçkun, Z., Güzel, S., Canacankatan, N., Yalaza, C., Kibar, D., & Yılmaz, B. C. (2018). Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats. In Drug and Chemical Toxicology (Vol. 43, Issue 1, pp. 104–111).
Yetkin, D., Ballı, E., Bayrak, G., Kibar, D., & Türkegün, M. (2018). The Investigation of the Effects of Tamoxifen and Vtamin D Combination on the Expression of P53,Bcl-2 and Bax and Cell Cycle in Mcf-7 Cell Line. In Proceedings (Vol. 2, Issue 25, pp. 1527-).
Vezir, Ö., Çömelekoğlu, Ü., Sucu, N., Yalın, A. E., Yılmaz, Ş. N., Yalın, S., Söğüt, F., Yaman, S., Kibar, D., Kibar, K., Akkapulu, M., Akkapulu, M., Koç, M. İ., & Seçer, D. (2017). N -Acetylcysteine-induced vasodilatation is modulated by K ATP channels, Na + /K + -ATPase activity and intracellular calcium concentration: An in vitro study. In Pharmacological Reports (Vol. 69, Issue 4, pp. 738–745).
Vezir, Ö., Çömelekoğlu, Ü., Sucu, N., Yalın, A. E., Yılmaz, Ş. N., Yalın, S., Söğüt, F., Yaman, S., Kibar, D., Kibar, K., Akkapulu, M., Akkapulu, M., Koç, M. İ., & Seçer, D. (2017). N -Acetylcysteine-induced vasodilatation is modulated by K ATP channels, Na + /K + -ATPase activity and intracellular calcium concentration: An in vitro study. In Pharmacological Reports (Vol. 69, Issue 4, pp. 738–745).
Vezir, Ö., Çömelekoğlu, Ü., Sucu, N., Yalın, A. E., Yılmaz, Ş. N., Yalın, S., Söğüt, F., Akkapulu, M., Yaman, S., Koç, M. İ., Kibar, K., Seçer, D., & Koç, M. (2017). N-Acetylcysteine-induced vasodilatation is modulated by KATP channels, Na/K-ATPase activity and intracellular calcium concentration: An in vitro study. In Pharmacological Reports (Vol. 69, Issue 4, pp. 738–745).
Söğüt, F., Yalçınkaya, A., Eroğlu, P., Samadı, A., Çömelekoğlu, Ü., Vezir, Ö., Lay, İ., Sucu, N., Ünal, S., Yalın, A. E., Akbıyık, F., Öztaş, Y. E., Yalın, S., Yılmaz, Ş. N., Yaman, S., Koç, M. İ., Kibar, D., Akkapulu, M., & Seçer, D. (2016). Increased plasma 7 ketocholesterol levels may explain the hypocholesterolemia of sickle cell disease patients. In The FEBS Journal (Vol. 283, Issue S1, pp. 57–126).
B. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings) basılan bildiriler (29)
Ünlügenç, A. T., Canacankatan, N., Antmen, Ş. E., Kibar, D., & Yılmaz, B. C. (2025). EFFECT OF RESVERATROL ON LIVER ON EXPERIMENTAL HYPERTHROIDCONDITIONED RATS. In ÇUKUROVA 15TH INTERNATIONAL SCIENTIFIC RESEARCHES CONGRESS.
Demirbağ, B., Ballı, E., Ünver, H., Kibar, D., Değirmenci, E., & Yılmaz, M. K. (2023). Investigation of the Anti-Cancer Effects of Photodynamic Therapy by Using the Schiff-Base Ligand Complex As Photosensitizers on Human Breast Cancer Cell Line. In International Conference on Global Practice of Multidisciplinary Scientific Studies-IV.
Demirbağ, H. O., Ballı, E., & Kibar, D. (2020). Prematür Over Yetmezliğinde Adipoz Kökenli Mezenkimal Kök Hücrelerin Folikülogenez Üzerine Etkilerinin İncelenmesi. In 8. Uluslararası Bilimsel Araştırmalar Kongresi-Fen ve Mühendislik Bilimleri (pp. 83–100).
Kibar, D., Yetkin, D., Oruç, H., & Yılmaz, Ş. N. (2020). 17β-Östradiol ve 1,25-Dihidroksi Vitamin D3 Uygulanan Düz Kas Hücrelerinde Çoğalma ve Apoptoz Dinamiklerinin Epigenetik Analizi. In 8. Uluslararası Bilimsel Araştırmalar Kongresi (pp. 73–81).
Söğüt, F., Uzun, C., Kibar, D., Çömelekoğlu, Ü., & Yılmaz, Ş. N. (2020). The Effect of Permethrin, A Type I Pyrethroid İnsecticide, on
Vascular Smooth Muscle KATP Channel Currents. In 5th International Mediterranean Science and Engineering Congress (IMSEC 2020) (pp. 666–666).
Reşitoğlu, M. T., Özşen, M., Yalçınkaya, Ü., Güden, D. S., Bilgen, S., Şenol, Ş. P., Vezir, Ö., Yazıcı, Z., Sucu, N., Kibar, D., Yılmaz, Ş. N., Tunçtan, B., & Fırat, S. Ş. (2020). mTOR contributes to cardiovascular injury caused by DOCA-salt administration in rats. In 5th International Hippocrates Congress on Medical and Health Sciences (pp. 495-).
Kaynar, A. H., Söğüt, F., Kibar, D., Yılmaz, Ş. N., & Çömelekoğlu, Ü. (2020). SiO2 nanoparçacıklarının insan retinal pigment epiteli TRPM2 kanal akımı üzerine etkisi. In 4. International Mersin Symposium.
Köse, E., Canacankatan, N., Dinç, E., Vatansever, M., Kibar, D., Yılmaz, B. C., & Erdoğan, S. (2019). Pterjium Patogenezinde Apoptozis ve Enflamasyon. In IV. Uluslararası Bilimsel ve Mesleki Çalışmalar Kongresi.
Güden, D. S., Reşitoğlu, M. T., Şenol, Ş. P., Kibar, D., Yılmaz, N. T., Yılmaz, Ş. N., Tunçtan, B., & Fırat, S. Ş. (2019). mTOR contributes to LPS-triggered neuroinflammation: Modulation of IκB-α/NF-κB/HIF-1α signaling pathway. In GERMAN PHARM-TOX SUMMIT (Vol. 392, Issue 1, pp. 6–6).
Yetkin, D., Ballı, E., Bayrak, G., & Kibar, D. (2018). Meme Kanseri Hücre Hattında Tamoksifen ve Vitamin D Kombinasyonunun Hücre Proliferasyonu ve Apoptoz Üzerine Etkilerinin Ġncelenmesi. In International Scientific Research Congress (UBAK).
Uçkun, Z., Kibar, D., Güzel, S., & Bayrak, G. (2018). OP-133: HISTOPATHOLOGICAL EFFECTS OF SILYMARIN IN THE LIVER TISSUES OF VANCOMYCIN-ADMINISTERED RATS. In 12th International Symposium on Pharmaceutical Sciences-ISOPS (pp. 113–114).
Canacankatan, N., Belveren, S., Poyraz, S., Yetkin, D., Kibar, D., Yılmaz, Ş. N., & Döndaş, H. A. (2018). The Effect of Functionalized Pyrrolidine-Indole Hybrid Heterocycles on VEGF in MCF-7 Cells. In 12 th International Symposium on Pharmaceutical Sciences (ISOPS-12) (pp. 346–346).
Uçkun, Z., Kibar, D., Güzel, S., & Bayrak, G. (2018). Histopathological effects of silymarin in the liver tissues of vancomycin-administered rats. In 12th International Symposium on Pharmaceutical Sciences-ISOPS (Vol. 121, pp. 113–114).
Yetkin, D., Ballı, E., Bayrak, G., Kibar, D., & Türkegün, M. (2018). The Investigation of the Effects of Tamoxifen and Vitamin D Combination on the Expression of P53, Bcl-2 and Bax and Cell Cycle in Mcf-7 Cell Line. In The 2nd International Cell Death Research Congress (Vol. 2, Issue 25, pp. 1527-).
Öztanrıverdi, O., Aşkın, A., Söğüt, F., Kibar, D., & Çömelekoğlu, Ü. (2018). Astemizol ve İmipraminin Prostat Kanseri Hücre Hattı Üzerine Sitotoksik Etkisi. In 1. Uluslararası Öğrenci Multidisipliner Akademik Çalışmaları Kongresi.
Teke, S., Çıtak, E. Ç., Bayrak, G., Kibar, D., & Yılmaz, Ş. N. (2018). The Evaluation of the Protective Activity of Angiotensin II Receptor Blocker Losartan Against Cisplatin Induced Nephrotoxicity in Mice. In 12th International Symposium on Pharmaceutical Sciences.
Kibar, K., Yılmaz, Ş. N., Yetkin, D., Temel, G. O., & Çömelekoğlu, Ü. (2017). The Epigenetic Analysis of the Effect of 17β-Estradiol and 1,25-Dihydroxyvitamin D3 on the Proliferation and Apoptosis Dynamics of Smooth Muscle Cells. In 15th International Congress of Histochemistry and Cytochemistry “From Molecules to Diseases.”
Karagül, M. İ., Aktaş, S., Yetkin, D., Kibar, K., Ovla, H. D., & Çelikcan, H. D. (2017). The Effect of Perifosine and Vitamin D Combination on Endometrial Cancer Cell Line (HEC1A). In 3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 (pp. 148-).
Uçkun, Z., Kibar, K., Güzel, S., & Yılmaz, B. C. (2017). Histopathological examination of the effects of silymarin on vancomycin-induced nephrotoxicity in rats. In 2nd International Gazi Pharma Symposium (pp. 50–50).
Kibar, K., Uçkun, Z., Güzel, S., & Yılmaz, B. C. (2017). Histopathological effects of naringenin on vancomycin-induced nephrotoxicity in rats. In International Multidisciplinary Symposium On Drug Research And Development (pp. 190–190).
Uçkun, Z., Kibar, K., Güzel, S., & Yılmaz, B. C. (2017). O 23 Histopathological Examination of The Effects of Silymarin on Vancomycin-Induced Nephrotoxicity in Rats. In 2nd International Gazi Pharma Symposium Series (GPSS-2017) (pp. 50–50).
Yılmaz, M., Kibar, K., Yılmaz, B. C., Gürses, İ., & Kıykım, A. A. (2017). The ultrastructural investigation of slit diaphram protein expressions and filtration barrier features in some human podocytopathies. In 15. International Congress Histochemistry and Cytochemistry.
Kibar, K., Uçkun, Z., Güzel, S., & Yılmaz, B. C. (2017). OP 09 Histopathological Effects of Naringenin on Vancomycin-induced Nephrotoxicity in Rats. In 3rd International Multidisciplinary Symposium on Drug Research and Development(DRD 2017) (pp. 190–190).
Demirbağ, B., Aktaş, S., Yıldırım, M., Çömelekoğlu, Ü., Yıldırım, D. D., & Kibar, K. (2017). The investigation of paricalcitol effects on testicular tissue exposed to subchronic 1800 MHz electromagnetic field. In 15th International Congress of Histochemistry and Cytochemistry “From Molecules to Diseases” (pp. 399–401).
Canacankatan, N., Belveren, S., Poyraz, S., Yetkin, D., Kibar, K., Yılmaz, Ş. N., & Döndaş, H. A. (2017). Effect of Pyrrolidine Derivatives Bearing Indole Ringas Substituted Moiety on COX2 on MCF-7 Cells. In 2nd International Gazi Pharma Symposium Series (GPSS-2017) (Issue O17).
Yılmaz, Ş. N., Yılmaz, N., Kibar, K., & Temel, G. O. (2017). EPIGENETIC ANALYSIS OF THE PROLIFERATION AND MATURATIONDYNAMICS OF OLIGODENDROCYTES IN PREGNANT ANIMALS IN AMODEL OF MULTIPLE SCLEROSIS. In FENS Regional Meeting.
Güzel, S., Uçkun, Z., Canacankatan, N., Antmen, Ş. E., Yalaza, C., Kibar, K., & Yılmaz, B. C. (2017). P 133 Investigation of Effects of Naringenin on Vancomycin-induced Nephrotoxicity in Rats. In 2nd International Gazi Pharma Symposium Series (GPSS-2017) (pp. 202–202).
Güzel, S., Uçkun, Z., Canacankatan, N., Antmen, E., Yalaza, C., Kibar, K., & Yılmaz, B. C. (2017). Investigation of effects of naringenin on vancomycin-induced nephrotoxicity in rats. In 2nd International Gazi Pharma Symposium (pp. 202–202).
Canacankatan, N., Belveren, S., Poyraz, S., Gemili, M., Yetkin, D., Kezban, K., Kibar, K., Nural, Y., Yılmaz, Ş. N., & Döndaş, H. A. (2016). Antiapoptotic Effect of Pyrrolidine Derivatives Bearing Indole Ring As Substituted Moiety on MCF 7 Cells. In 4th International Bahçeşehir University (BAU) Drug Design Congress.
E. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler (3)
Gürler, H. M., Canacankatan, N., Kibar, D., Erdoğan, S., & Yılmaz, B. C. (2020). Deneysel Hipertiroidi Oluşturulmuş Sıçanlarda Resveratrolün Kalp Üzerinde Etkisi. In 31. Ulusal Biyokimya Kongresi.
Uçkun, Z., Güzel, S., Kibar, K., & Yılmaz, B. C. (2017). Sıçanlara günde bir kez ve günde iki kez uygulanan vankomisinin nefrotoksisitesindeki farklılılar. In 1. Anadolu Üniversitesi Eczacılık Sempozyumu (AnES) (pp. 35–35).
Uçkun, Z., Güzel, S., Kibar, D., & Yılmaz, B. C. (2017). S 17 Sıçanlara Günde Bir Kez Ve Günde İki Kez Uygulanan Vankomisinin Nefrotoksisitesindeki Farklılıklar. In 1. Anadolu Üniversitesi Eczacılık Fakültesi Sempozyumu (pp. 35–35).
B. Ulusal Projeler (2)
Fare Hipokampusunda Nörojenik Niş Elemanı Olarak Astrositlerin, Gebelik ve Sonrası Dönemde Nörogeneze Etkilerinin İncelenmesi, ARAŞTIRMA PROJESİ, Araştırmacı, 05.06.2017 -
Östrojen Ve Progesteronun Safen Ven Düz Kas Hücreleri Üzerindeki Proliferatif, Migratif Ve İnvaziv Etkilerinin In Vitro Olarak Araştırılması (217S214), -Tübitak 3001, Araştırmacı, 01.03.2018 - 01.09.2019
Oluşturma Tarihi:
17.12.2025 16:01