Exploring bisbenzimidazole-chalcone hybrid compounds: Dual-action as antibacterial agents targeting biofilm formation and E. coli DNA gyrase inhibition
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Development of Benzoxazole Derivatives Targeting mTOR: A Promising Approach for Breast Cancer Therapy
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Mehmet Abdullah Alagöz, Meryem Temiz Reşitoğlu, Burak Kuzu, Derya Yetkin, Cengiz Zobi, Rukiye Nalan ...
Development of Potent Type V MAPK Inhibitors: Design, Synthesis, and Biological Evaluation of Benzothiazole Derivatives Targeting p38α MAPK in Breast Cancer Cells
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Bayan Zoatier, Kübra Gizem Yıldıztekin, Mehmet Abdullah Alagöz, Ceylan Hepokur, Serdar Burmaoğlu, Öz...
Design, Synthesis, and In Silico Analyses of Nitroimidazole Derivatives Targeting Cholinesterases
CHEMISTRYSELECT, vol. 10, no. 35, pp. –
Büşra Bıyık, Ayşe Hande Tarikoğulları Doğan, Mehmet Abdullah Alagöz, Yeliz Demir, İlhami Gülçin, Özt...
Synthesis and evaluation of sulfonamide-chalcone hybrid compounds as inhibitors of VEGFR1/VEGFR2-mediated angiogenesis
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Neslişah Barlak, Fatma Şanlı, Süleyman Çelik, Burhan İskender, Derya Aktaş, Nicola Gambacorta, Serda...
Substituted bisbenzimidazole derivatives as multiple targeting agents to treat Alzheimer's disease, diabetes, and microbial infections
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Öztekin Algül, Burak Mete, Burçin Türkmenoğlu, Rüya Sağlamtaş, Mehmet Abdullah Alagöz, M.abdullah Al...
Design and synthesis of new HCV NS3/4A protease inhibitors to effective against drug resistance
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Zehra Öksüz, Mine Buğa Aktekin, Mine Buga Aktekin, Mehmet Abdullah Alagöz, Mehmet Kuzucu, Mehmet Sam...
Structure-based inhibition of acetylcholinesterase and butyrylcholinesterase with 2-Aryl-6-carboxamide benzoxazole derivatives: synthesis, enzymatic assay, and in silico studies
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Burak Kuzu, Mehmet Abdullah Alagöz, Yeliz Demir, İlhami Gülçin, Serdar Burmaoğlu, Öztekin Algül
The Significance of Mono- and Dual-Effective Agents in the Development of New Antifungal Strategies
CHEMICAL BIOLOGY & DRUG DESIGN, vol. 105, no. 1, pp. –
Cengiz Zobi, Öztekin Algül
Benzoxazole Derivatives as Dual p38α Mitogen-Activated Protein Kinase and Acetylcholinesterase Inhibitors: Design, Synthesis, and Evaluation for Alzheimer's Disease and Cancer Therapy
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Bayan Zoatier, Kübra Gizem Yıldıztekin, Mehmet Abdullah Alagöz, Ceylan Hepokur, Esra Dilek, Öztekin ...
Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells
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Burak Kuzu, Derya Yetkin, Ceylan Hepokur, Öztekin Algül
Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
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Serdar Burmaoğlu, Arzu Göbek, Derya Aktaş Anıl, Mehmet Abdullah Alagöz, Adem Güner, Cem Güler, Ceyla...
From Deep Learning to the Discovery of Promising VEGFR-2 Inhibitors
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Hydrazide-Bridged Pyridazines for Cholinesterase Inhibitors: Synthesis, Characterizations, In Silico, and In Vitro Evaluation
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The Future of Innovative Drug Discovery: Integrating Dual Inhibition and Artificial Intelligence
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Mehmet Ali Yücel, Öztekin Algül
Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone-Cu Complexes
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Rüstem Ebiri, Muhammet Turgut, Derya Aktaş, Derya Aktaş Anıl, Yeliz Demir, Rüya Sağlamtaş, Mehmet Ab...
Exploring new 5-Nitroimidazole Derivatives as Potent Acetylcholinesterase and Butyrylcholinesterase Enzyme Inhibitors
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Şule Gürsoy, Doruk Satıcı, Burak Kuzu, Burçin Türkmenoğlu, Esra Dilek, Öztekin Algül
Synthesis and evaluation of di-heterocyclic benzazole compounds as potential antibacterial and anti-biofilm agents against Staphylococcus aureus
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Synthesis and antitubercular activities of acetamide-substituted benzazole derivatives
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Şule Gürsoy, Elif Şevval Öztürk, Bayan Zoatier, Mahmut Ülger, Öztekin Algül
Deep learning approach to the discovery of novel bisbenzazole derivatives for antimicrobial effect
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Tunga Barçın, Tunga Barcın, Mehmet Ali Yücel, Ronak Haj Ersan, M Alagöz, Mehmet Abdullah Alagöz, Ayl...
N-(benzazol-2-yl)-2-substituted phenylacetamide derivatives: Design, synthesis and biological evaluation against MCF7 breast cancer cell line
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Bayan Zoatier, Metin Yıldırım, Mehmet Abdullah Alagöz, Derya Yetkin, Burçin Türkmenoğlu, Serdar Burm...
Design, synthesis, and computational studies of benzimidazole derivatives as new antitubercular agents
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Machine learning study: from the toxicity studies to tetrahydrocannabinol effects on Parkinson's disease
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Mehmet Ali Yücel, İbrahim Özçelik, Öztekin Algül
New Fluoro- and Trifluoromethyl-Substituted Trimethoxychalcones as Anticancer Agents: Synthesis, Bio-evaluation, and Computational Studies
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Muhammed Fatih Polat, Derya Aktaş Anıl, Kübra Gizem Yıldıztekin, Burçin Türkmenoğlu, Ceylan Hepokur,...
Synthesis, molecular docking and some metabolic enzyme inhibition properties of biphenyl-substituted chalcone derivatives
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Design, synthesis and in vitro antiproliferation activity of some 2-aryl and -heteroaryl benzoxazole derivatives
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Burak Kuzu, Ceylan Hepokur, Burçin Türkmenoğlu, Serdar Burmaoğlu, Öztekin Algül
Synthesis, Biological Evaluation and In Silico Studies of Some 2-Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
CHEMISTRYSELECT, vol. 7, no. 1, pp. –
Burak Kuzu, Ceylan Hepokur, Mehmet Abdullah Alagöz, Serdar Burmaoğlu, Öztekin Algül
Exploring enzyme inhibition profiles of novel halogenated chalcone derivatives on some metabolic enzymes: Synthesis, characterization and molecular modeling studies
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Derya Anıl, Muhammed Fatih Polat, Rüya Sağlamtaş, Ayşe Hande Tarikoğulları Doğan, Mehmet Abdullah Al...
Synthesis, In Vitro Biological Evaluation, and Molecular Docking Studies of Novel Biphenyl Chalcone Derivatives as Antimicrobial Agents
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Serdar Burmaoğlu, Elif Akın Kazancıoğlu, Mustafa Kazancıoğlu, Mustafa Zahrittin Kazancıoğlu, Mehmet ...
Bisbenzoxazole Derivatives: Design, Synthesis, in Vitro Antimicrobial, Antiproliferative Activity, and Molecular Docking Studies
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Ronak Haj Ersan, Mehmet Abdullah Alagöz, Mehmet Alagöz, Aylin Döğen, Nizami Duran, Serdar Burmaoğlu,...
2-Phenyl substituted Benzimidazole derivatives: Design, synthesis, and evaluation of their antiproliferative and antimicrobial activities
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Ronak Haj Ersan, Burak Kuzu, Derya Yetkin, Mehmet Abdullah Alagöz, Mehmet Alagöz, Aylin Döğen, Serda...
Bisbenzimidazole Derivatives as Potential Antimicrobial Agents: Design, Synthesis, Biological Evaluation and Pharmacophore Analysis
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Ronak Haj Ersan, Kayhan Bolelli, Serpil Gonca, Aylin Döğen, Serdar Burmaoğlu, Öztekin Algül
New chalcone derivatives as effective against SARS-CoV-2 agent
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Nizami Duran, Muhammed Fatih Polat, Derya Anıl, Mehmet Abdullah Alagöz, Emrah Ay, Funda Çimen, Erhan...
Synthesis of Benzoxazole-2-carboxylate Derivatives: Electronic- and Position-effect of Functional Groups and Computational Modeling of the Selectivity for Oxazole Ring
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Burak Kuzu, Özlem Sarı, Nurettin Sağ Erdem, Öztekin Algül, Nurettin Mengeş
Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes
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Synthesis and biological evaluation of 3,5-diaryl-pyrazole derivatives as potential antiprostate cancer agents
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Derya Anıl, Emine U. Çayköylü, Fatma Şanlı, Nicola Gambacorta, Ömer Faruk Karataş, Orazio Nicolotti,...
Design, synthesis and biological evaluation of novel bischalcone derivatives as potential anticancer agents
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Serdar Burmaoğlu, Arzu Göbek, Büşra Öztürk Aydın, Emine Yurtoğlu, Buşra Nur Aydın, Gözde Yalçın, Cey...
An efficient synthesis of novel di-heterocyclic benzazole derivatives and evaluation of their antiproliferative activities
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Öztekin Algül, Ronak Haj Ersan, Mehmet Abdullah Alagöz, Mehmet Abdullah Alagoz, Nizami Duran, Serdar...
Head-to-head bisbenzazole derivatives as antiproliferative agents: design, synthesis, in vitro activity, and SAR analysis
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Ronak Haj Ersan, Mehmet Abdullah Alagöz, Tuğba Ertan Bolelli, Nizami Duran, Serdar Burmaoğlu, Özteki...
One‐pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies
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Ronak Haj Ersan, Ahmet Yüksel, Tuğba Ertan Bolelli, Aylin Döğen, Serdar Burmaoğlu, Öztekin Algül
New-Generation Benzimidazole-Based Plasmid Delivery Reagents with High Transfection Efficiencies on the Mammalian Cells
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, vol. 56, no. 1, pp. 34–41
Furkan Ayaz, Ersan Ronak Haj, Burak Kuzu, Öztekin Algül
Design, synthesis and biological evaluation of 3,5-diaryl isoxazole derivatives as potential anticancer agents
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Derya Anıl Aktas, Derya Anıl, Gökçen Akınalp, Fatma Sanlı, Fatma Sanlıalp, Mehmet Ali Yucel, Mehmet ...
Design, synthesis and antiproliferative activity evaluation of fluorine-containing chalcone derivatives
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Synthesis of novel organohalogen chalcone derivatives and screening of their molecular docking study and some enzymes inhibition effects
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Serdar Burmaoğlu, Elif Akın Kazancıoğlu, Rüya Kaya, Mustafa Zahrittin Kazancıoğlu, Muhammet Karaman,...
Symmetric bis-benzoxazole-based chemicals exerted anti-inflammatory effect on danger signal LPS-stimulated macrophages
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Furkan Ayaz, Ersan Ronak Haj, Öztekin Algül
Bisbenzoxazole derivatives had an antiinflammatory effect on in vitro stimulated macrophages
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Furkan Ayaz, Kheeree Rusmeenee, Isse Qadar Ahmed, Ersan Ronak Haj, Öztekin Algül
Synthesis of New Alicyclic Oxalamide Derivatives and Their Differential Immunomodulatory Activities on the Mammalian Cells
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Burak Kuzu, Furkan Ayaz, Öztekin Algül
BISBENZOXAZOLE DERIVATIVES HAD ANTI-PROLIFERATIVE EFFECT ON HUMAN CANCER CELLS
Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi C- yaşam Bilimleri ve Biyoteknoloji (Online), vol. 8, no. 2, pp. 203–211
Furkan Ayaz, Isse Qadar Ahmed, Kheeree Rusmeenee, Ersan Ronak Haj, Öztekin Algül
Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors
BIOORGANIC CHEMISTRY, vol. 85, no. null, pp. 191–197
İlhami Gülçin, Serdar Burmaoğlu, Rüya Kaya, Ali Osman Yılmaz, Öztekin Algül, Muhammed Fatih Polat, M...
Immunomodulatory and immunostimulatory effects of some bisbenzoxazole derivatives on lipopolysaccharide stimulated mammalian macrophages
JOURNAL OF RESEARCH IN PHARMACY, vol. 23, no. 5, pp. 944–951
Furkan Ayaz, Isse Qadar Ahmed, Kheeree Rusmeenee, Ersan Ronak Haj, Öztekin Algül
Antiviral ilaçlardaki gelişmeler ve değerlendirilmesi
Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, vol. 9, no. 2, pp. 160–170
Banpiny Pal Wath Dar, Zehra Öksüz, Öztekin Algül
Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents
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Serdar Burmaoğlu, Şeyda Özcan, Sevgi Balcıoğlu, Melis Gencel, Samır Abbas Alı Noma, Şebnem Eşsiz Gök...
Molecular docking studies on fluoro-substituted chalcones as potential DprE1 enzyme inhibitors
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Gözde Yalçın, Gozde Yalcın, Serdar Burmaoğlu, İlkay Yıldız, Öztekin Algül
Synthesis and biological evaluation of phloroglucinol derivatives possessing -glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity
ARCHIV DER PHARMAZIE, vol. 351, no. 2, pp. 1–12
Serdar Burmaoğlu, Ali Osman Yılmaz, Parhimi Taslimi, Öztekin Algül, Deryanur Kılç, İlhami Gülçin
Design of potent fluoro-1substituted chalcones as antimicrobial agents
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Serdar Burmaoğlu, Öztekin Algül, Arzu Gobek, Arzu Göbek, Derya Aktaş Anıl, Anil Derya Aktas, Mahmut ...
Synthesis and anti-proliferative activity of fluoro-substituted chalcones
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Serdar Burmaoglu, Öztekin Algül, Derya Aktaş Anıl, Arzu Göbek, Gülay Gülbol Duran, Ronak Haj Ersan, ...
Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, no. sup4, pp. 20–24
Kaan Kucukoglu, Fatih Oral, Tevfik Aydın, Cem Yamali, Öztekin Algül, Hiroshi Sakagami, İlhami Gulcin...
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Synthesis and antimicrobial activity evaluation of some benzimidazole and indole derivatives
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Nafize Didem Yüksek, Öztekin Algül, Tari Özden, Aylin Döğen, Özden Tarı, Küçük Emrah, Emrah Küçük, O...
Apoptotic and anti angiogenic effects of benzimidazole compounds relationship with oxidative stress mediated ischemia reperfusion injury in rat hind limb
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Öztekin Algül, Karabulut Alper, Necmiye Canacankatan, Ayşegül Görür, Nehir Sucu, O Vezir
2-(4-Methoxy-2-methylanilino)-1,2-diphenylethanone
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Hakan Arslan, Öztekin Algül, Selin Zirek, Tarı Ozden, Özden Tarı, Aydın Demircan, Kenneth Hardcastle...
2 4 Diamino 5 2 arylpropargyl pyrimidine derivatives as new nonclasical antifolates for human dihydrofolate reductase inhibition
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Öztekin Algül, Janet L Paulsen, Amy C Anderson
Comparative studies on conventional and microwave-assisted synthesis of a series of 2,4-di and 2,3,4-trisubstituted benzimidazol[1,2-a] pyrimidines and their antimicrobial activities
CENTRAL EUROPEAN JOURNAL OF CHEMISTRY, vol. 7, no. 3, pp. 337–342
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Design synthesis and biological evaluation of bis hydroxyphenyl azoles as potent and selective non steroidal inhibitors of 17b hydroxysteroid dehydrogenase type 1 17b HSD1 for the treatment of estrogen dependent diseases
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Emmanuel Bey, Sandrıne Marchaısoberwınkler, Patrıca Kructhen, Martın Frotscher, Ruht Werth, Alexande...
Vibrational spectrum and assignments of 2-(4-methoxyphenyl)-1 H-benzo[d]imidazole by ab initio Hartree-Fock and density functional methods
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Hakan Arslan, Öztekin Algül
Vibrational spectroscopy investigation using ab initio and density functional theory analysis on the structure of 3-(6-benzoyl-2-oxobenzo[d]oxazol-3(2H)-yl)propanoic acid
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, vol. 70, no. 3, pp. 606–614
Hakan Arslan, Öztekin Algül, Tijen Önkol
Structural and spectral studies on,3-(6-benzoyl-5-chloro-2-benzoxazolinon-3-yl) propanoic acid
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Hakan Arslan, Öztekin Algül, Yasemin Dündar
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Andre Kaessler, Oztekın Algul, Joachım Jose
Activity of bisbenzimidazoles derivatives to Staphylococcus epidermidis
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Algul Oztekin, Duran Nizami
Synthesis and Ab Initio/DFT Studies on 2-(4-methoxyphenyl)benzo[d]thiazole
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Theoretical studies of molecular structure and vibrational spectra of 2-ethyl-1H-benzo[d]imidazole
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Arslan Hakan, Algul Oztekin
Synthesis and evaluation of antimicrobial activity of some 1,5(6)-H/or -methyl-2-subtituted benzimidazole derivatives
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Assessment of availability and factors affecting purchase of flu medicine in Turkey
Pharmacia, vol. 52, no. 1, pp. 222–224
Erdaş Burcu, Nefise Özlen Şahin, Yüksel Altan, Öztekin Algül, Uca İmren
Synthesis cytotoxic activity on MCF 7 cell line and mutagenic activity of platinum II complexes with 2 substituted benzimidazole ligands
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 38, no. 38, pp. 473–480
Fatma Gümüş, Öztekin Algül, Gökçen Eren, Burtay Hatice Eroğlu, Nuran Diril, Sibel Gür, Aykut Özkul
DNA Binding Studies with cis Dichlorobis 5 6 non chlorosubstituted 2 hydroxymethyl benzimidazole Platinum II Complexes
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Effect of Benzimidazole Compound on Endoplasmic Reticulum Stress and Unfolded Protein Response (UPR) Signaling Pathway in Hydrogen Peroxide (H2O2)-Induced BEAS-2B Cells
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Novel oxalamide derivatives for COXs expression and breast cancer: design, synthesis, biological evaluation, and docking studies
ORGANIC COMMUNICATIONS, vol. 16, no. 3, pp. 152–165
Burak Kuzu, Ceylan Hepokur, Öztekin Algül
DNA Base Bioisosteres, Bis-benzoxazoles, Exert Anti-proliferative Effect on Human Prostate and Breast Cancer Cells
Journal of the Turkish Chemical Society, Section A: Chemistry, vol. 5, no. 3, pp. 1145–1152
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Synthesis Characterization and Genotoxicity of Platinum II Complexes with Benzimidazole Ligands
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Öztekin Algül, Berrin Özçelik, Ufuk Abbasoğlu, Fatma Gümüş
Revisit to the synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives in lactic acid media as a green solvent and catalyst
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Akbaslar Dilek, Giray E. Sultan, Algul Oztekin
Investigation of New Benzimidazole Derivative Compounds' Effects on A549 Cell Line
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Synthesis and Antifungal Evaluation of 1-Aryl-2-dimethylaminomethyl-2-propen-1-one Hydrochlorides
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A microplate based screening of benzimidazole derivatives on hyaluronidase inhibition at PH 7 and 3.5
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