Non-ST elevasyonlu miyokard infarktüsü hastalarında potansiyel bir biyobelirteç olan salusin beta düzeyinin rolü

Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 17, no. 1, pp. 75–83

Ali Orçun Sürmeli, Özcan Örsçelik, Buğra Özkan, İsmail Türkay Özcan, Mehmet Burak Yavuz Çimen, Müslü...

2025 Hakemli DOAJ Link
Relationship Between Urinary Angiotensinogen and Mortality in Patients with Heart Failure with Reduced Ejection Fraction

ANATOLIAN JOURNAL OF CARDIOLOGY, vol. 27, no. 7, pp. 417–422

Özcan Örsçelik, Emrah Yeşil, Ali Orçun Sürmeli, Buğra Özkan, Mehmet Burak Yavuz Çimen

2023 Hakemli SCI-Expanded Q4 Link
Aspirin use in patients aged 80 and over: Snapshot of the results from the ASSOS study in the cardiology outpatient clinic setting in Turkey

The Anatolian Journal of Family Medicine, vol. , no. , pp. –

Kadriye Memiç Sancar, Oğuzhan Çelik, Cem Çil, Özcan Başaran, Erkan Demirci, Veysel Ozan Tanık, Mücah...

2022 Hakemli DOAJ Link
A comparison of the effects of ticagrelor and clopidogrel on development of no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction

Mersin Universitesi Saglik Bilimleri Dergisi, vol. 15, no. 2, pp. 196–206

Emrah Yeşil, Hakan Uyar, Hakan Uyar, Özcan Örsçelik, Buğra Özkan, Ahmet Çelik, İsmail Türkay Özcan, ...

2022 Hakemli DIRECTORY OF OPEN ACCESS JOURNALS (DOAJ) Link
Study of Transesophageal Echocardiography in Young Patients with Cryptogenic Stroke: Prevalence of Patent Foramen Ovale and Interpretation of the RoPE Score

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, vol. 50, no. 5, pp. 314–319

Ayça Arslan, Dilek Çiçek Yılmaz, Muhammed Adıyaman, Celal Kara, Özcan Örsçelik, İbrahim Arda Yılmaz

2022 Hakemli Emerging Sources Citation Index 1 atıf Link
A Novel Indicator of Myocardial Injury after Acute Myocardial Infarction: 'DPP-3'

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol. 28, no. , pp. 107602962211451–

Özge Özden, Cuma Yeşildaş, Mustafa Demir, Ali Orçun Sürmeli, Emrah Yeşil, Özcan Örsçelik, Ahmet Çeli...

2022 Hakemli SCI-Expanded Q3 1 atıf Link
An Evaluation of Aspirin Treatment Preferences ORIGINAL INVESTIGATION of Physicians in Hypertensive Patients in Terms of Current Guidelines: A Subgroup Analysis of the ASSOS Trial in Turkey.

Anatolian journal of cardiology, vol. 26, no. 4, pp. 260–268

Kadriye Memiç Sancar, Oğuzhan Çelik, Cem Çil, Osman Karaarslan, Tolga Doğan, Mücahit Yetim, Ramazan ...

2022 Hakemli SCI-Expanded Q4 1 atıf Link
The effect of ferric carboxymaltose treatment on the TP-E interval and the TP-E/QT and TP-E/QTc ratios in heart failure patients with iron deficiency

KARDIOLOGIYA, vol. 62, no. 10, pp. 42–48

Emrah Yeşil, Hakan Uyar, Özcan Örsçelik, Buğra Özkan, Mustafa Demir, Cuma Yeşildaş, İsmail Türkay Öz...

2022 Hakemli SCI-Expanded Q4 Link
Cardiac Chamber Quantification by Echocardiography in Adults With Sickle Cell Disease: Need Attention to Eccentric Hypertrophy

CUREUS JOURNAL OF MEDICAL SCIENCE, vol. 13, no. 6, pp. 1–8

Mahmut Bakır Koyuncu, Anıl Tombak, Özcan Örsçelik, Tolga Köşeci, Ali Türker, Hakan Basır, Aydan Akde...

2021 Hakemli PubMed Central (PMC), PubMed, Google Scholar and Web of Science... Link
Inappropriate Use of Aspirin in Real-Life Cardiology Practice: Results from the Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) Study

BALKAN MEDICAL JOURNAL, vol. 38, no. 3, pp. 183–189

Oğuzhan Çelik, Cem Çil, Özcan Başaran, Erkan Demirci, Veysel Ozan Tanık, Emine Altuntaş, Kadriye Mem...

2021 Hakemli SCI-Expanded Q3 2 atıf Link
Evaluation of the effect of percutaneous mitral balloon valvuloplasty on left ventricular systolic functions using strain and strain rate echocardiography

TURKISH JOURNAL OF MEDICAL SCIENCES, vol. 50, no. 4, pp. 724–730

Ertuğrul Emre Güntürk, Baran Oğuzhan, Hasan Akkaya, Özcan Örsçelik

2020 Hakemli SCI-Expanded Q4 2 atıf Link
The Effect of High Lactate Level on Mortality in Acute Heart Failure Patients With Reduced Ejection Fraction Without Cardiogenic Shock

Cardiovascular Toxicology, vol. 20, no. 4, pp. 361–369

Emrah Yesil, Emrah Yeşil, Muzaffer Karadeniz, Özcan Örsçelik, Buğra Özkan, İsmail Türkay Özcan, Dile...

2020 Hakemli SCI-Expanded Q2 7 atıf Link
Migrated thrombus extending from right atrium to left atrium through patent foramen ovale: Two case reports

Medicine Science, vol. 8, no. 0, pp. 1–758

Özcan Örsçelik, Emre Ertan Şahin, Emre Ertan Sahin, Emrah Yeşil, Buğra Özkan, Hakan Uyar, Dilek Çiçe...

2019 Hakemli DIRECTORY OF OPEN ACCESS JOURNALS (DOAJ) Link
Association with serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris

The Anatolian Journal of Cardiology, vol. 22, no. 5, pp. 250–255

Buğra Ozkan, Bugra Ozkan, Buğra Özkan, Özcan Örsçelik, Özcan Orsçelik, Hatice Yıldırım Yaroğlu, Şena...

2019 Hakemli SCI-Expanded Q4 3 atıf Link
Association between heart rate turbulence and anxiety symptom levels

Medicine Science International Medical Journal, vol. 8, no. 0, pp. 1–147

Buğra Özkan, Özcan Örsçelik, Cevahir Özkan, Mert Koray Özcan, Ayça Arslan, Ahmet Çelik, İsmail Türka...

2018 Hakemli TR DİZİN Link
The contribution of implantable cardioverter defibrillators to systemic inflammation in heart failure patients

Medicine Science International Medical Journal, vol. 8, no. 0, pp. 1–286

Özcan Örsçelik, Buğra Özkan, Mert Koray Özcan

2018 Hakemli doaj, scopemed, drji, sindex Link
The association of iron deficiency in patients with different types of heart failure

, vol. 20, no. S1, pp. 5–638

Ahmet Çelik, Özcan Örsçelik, Emre Ertan Şahin, Hakan Uyar, İsmail Türkay Özcan

2018 29 atıf Link
Awareness of Pleiotropic and Cardioprotective Effect of Statins in Patients with Coronary Artery Disease

BioMed Research International, vol. 2018, no. , pp. 1–7

Buğra Özkan, Özcan Örsçelik, Hakan Uyar, Mehmet Ballı, Eren Güçer, Onur Aslan, Gülhan Orekici Temel,...

2018 Hakemli SCI-Expanded 5 atıf Link
Varying AV Block Induced by Oxcarbazepine

Turkish Journal Of Neurology, vol. 24, no. 3, pp. 281–282

Özcan Örsçelik, Buğra Özkan, Emre Ertan Şahin, Ozan Sakarya, Ahmet Çelik, Mehmet Necdet Akkuş, İsmai...

2018 Hakemli ESCI, DOAJ, CAS, Index Copernicus 1 atıf Link
Relationship between intrarenal renin-angiotensin activity and re-hospitalization in patients with heart failure with reduced ejection fraction

The Anatolian Journal of Cardiology, vol. 19, no. 3, pp. 205–212

Özcan Örsçelik, Buğra Özkan, Ayça Aslan, Ayça Arslan, Emre Ertan Şahin, Ozan Sakarya, Ali Orçun Sürm...

2018 Hakemli SCI-Expanded 2 atıf Link
VASOPRESSIN-RELATED COPEPTIN IS A NOVEL PREDICTOR OF EARLY ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH ADULT POLYCYSTIC KIDNEY DISEASE

, vol. 32, no. suppl_3, pp. iii104–iii104

İsmail Koçyiğit, Mahmut Yılmaz, Güngör Özkan, Eray Eroğlu, Aydın Ünal, Özcan Örsçelik, Bülent Tokgöz...

2017 Link
Mobile thrombus extending from the distal segment of the left main coronary artery to the left anterior descending artery

Interventional Cardiology, vol. 09, no. 04, pp. 129–130

Özcan Örsçelik, Buğra Özkan, Emre Ertan Şahin, Veli Gökhan Cin, Mehmet Necdet Akkuş, İsmail Türkay Ö...

2017 Hakemli Scopus, EMBASE/Excerpta Medica Link
Vasopressin-related copeptin is a novel predictor of early endothelial dysfunction in patients with adult polycystic kidney disease

BMC Nephrology, vol. 17, no. 1, pp. –

İsmail Koçyiğit, Mahmut İlker Yılmaz, Özkan Güngör, Eray Eroğlu, Aydın Ünal, Özcan Örsçelik, Bülent ...

2016 Hakemli SCI-Expanded 7 atıf Link
Atrial electromechanical delay and left atrial mechanical functions in hemodialysis and peritoneal dialysis patients

International Urology and Nephrology, vol. 48, no. 5, pp. 781–789

Levent Demirtas, Kultigin Turkmen, Mutlu Buyuklu, İsmail Koçyiğit, Özcan Örsçelik

2016 Hakemli SCI-Expanded 4 atıf Link
The relationship of patent foramen ovale location with severity of stroke A new risk factor for paradoxical embolism

Acta Clinica Belgica, vol. 71, no. 3, pp. 149–153

Mustafa Fatih Erkoç, Bilge Öztoprak, Aylin Okur, Hüseyin Ede, Özcan Örsçelik, Abdulmecit Kantarcı, Y...

2016 Hakemli SCI-Expanded 1 atıf Link
Effects of influenza vaccination in patients with heart failure

Herz, vol. 42, no. 3, pp. 325–326

Ahmet Çelik, Özcan Örsçelik

2016 Hakemli SCI Link
Androgenetic alopecia as an indicator of metabolic syndrome and cardiovascular risk

Blood Pressure, vol. 25, no. 3, pp. 141–148

Ragıp Ertaş, Özcan Örsçelik, Demet Kartal, Ali Doğan, Sule Ketenci Ertas, Ebru Guler Aydogdu, Özcan ...

2016 Hakemli SCI 17 atıf Link
Effects of Dialysis Solution on the Cardiovascular Function in Peritoneal Dialysis Patients

Internal Medicine, vol. 54, no. 1, pp. 3–10

İsmail Koçyiğit, Aydın Ünal, Ozkan Gungor, Özcan Örsçelik, Eray Eroglu, Ender Dogan, Ahmet Sen, Must...

2015 Hakemli SCI-Expanded 2 atıf Link
Serum paraoxonase activity is associated with epicardial fat tissue in renal transplant recipients

International Urology and Nephrology, vol. 47, no. 8, pp. 1409–1414

Eray Eroglu, İsmail Koçyiğit, Aydın Ünal, Hafsa Korkar, Cigdem Karakukcu, Özcan Örsçelik, Murat Hayr...

2015 Hakemli SCI-Expanded 3 atıf Link
The Serum YKL-40 Level is Associated with Vascular Injury and Predicts Proteinuria in Nephrotic Syndrome Patients

Journal of Atherosclerosis and Thrombosis, vol. 22, no. 3, pp. 257–264

İsmail Koçyiğit, Ozkan Gungor, Ender Dogan, Serhat Karadavut, Cigdem Karakukcu, Eray Eroglu, Özcan Ö...

2015 Hakemli SCI-Expanded 8 atıf Link
Predictive Value of Atrial Electromechanical Delay on Long Term Cardiovascular Outcomes in Hemodialysis Patients

American Journal of Nephrology, vol. 42, no. 3, pp. 239–249

Kultigin Turkmen, Levent Demirtas, Ergun Topal, Abduzhappar Gaipov, Ismail Kocyigit, Özcan Örsçelik,...

2015 Hakemli SCI 3 atıf Link
The effect of prophylactic migraine treatment on arterial stiffness

Blood Pressure, vol. 24, no. 4, pp. 222–229

Ali Doğan, Özcan Örsçelik, Merva Kocyigit, Deniz Elcik, Oguzhan Baran, Nebi Cerit, Mehmet Tugrul Ina...

2015 Hakemli SCI 7 atıf Link
Takotsubo Cardiomyopathy: A Challenging Diagnosis for Emergency Service Clinicians!

Journal of Cardiology Current Research, vol. 1, no. 4, pp. –

Umut Ocak, Ömer Levent Avşaroğulları, Özcan Örsçelik, Tayfun Öztürk, N Doğan Kaymaz, Ayşe Ertekin, D...

2014 Hakemli Endekste taranmıyor Link
A Low Serum Free Triiodothyronine Level is Associated with Epicardial Adipose Tissue in Peritoneal Dialysis Patients

Journal of Atherosclerosis and Thrombosis, vol. 21, no. 10, pp. 1066–1074

İsmail Koçyiğit, O Gungor, Aydın Ünal, M Yasan, Özcan Örsçelik, Onur Tunca, E Eroglu, Murat Hayri Si...

2014 Hakemli SCI-Expanded 7 atıf Link
The effect of strict volume control on cardiac biomarker and arterial stiffness in peritoneal dialysis patients

Clinical Nephrology, vol. 81, no. 04, pp. 238–246

İsmail Koçyiğit, Ozkan Gungor, Aydın Ünal, Özcan Örsçelik, Eray Eroglu, Onur Tunca, Murat Hayri Sipa...

2014 Hakemli SCI 6 atıf Link
The relationship of location of patent foramen ovale with severity of stroke a life saving radiological approach

, vol. , no. , pp. –

M F Erkoc, Özcan Örsçelik, B Öztoprak, A Okur, M Kantarcı, Y Kizrak

2014 Link
Pentraxin 3 as a novel bio-marker of inflammation and endothelial dysfunction in autosomal dominant polycystic kidney disease

Journal of Nephrology, vol. 27, no. 2, pp. 181–186

İsmail Koçyiğit, Eray Eroglu, Özcan Örsçelik, Aydın Ünal, Ozkan Gungor, Fahir Ozturk, Cigdem Karakuk...

2014 Hakemli SCI-Expanded 16 atıf Link
The Association Between Arterial Stiffness And Fluid Status in Peritoneal Dialysis Patients

Peritoneal Dialysis International, vol. 34, no. 7, pp. 781–790

Kocyigit Ismail, Sipahioglu Murat Hayri, Orscelik Ozcan, Unal Aydin, Celik Ahmet, Abbas Samer R, Zhu...

2014 Hakemli SCI 29 atıf Link
Serum Uric Acid Levels and Endothelial Dysfunction in Patients with Autosomal Dominant Polycystic Kidney Disease

Nephron Clinical Practice, vol. 123, no. 3-4, pp. 157–164

Ismail Kocyigit, Mahmut Ilker Yilmaz, Özcan Örsçelik, Murat Hayri Sipahioglu, Aydin Unal, Eray Erogl...

2013 Hakemli SCI-Expanded 27 atıf Link
Bilirubin Levels and the Burden of Coronary Atherosclerosis in Patients With STEMI

Angiology, vol. 64, no. 3, pp. 200–204

O Sahin, Mahmut Akpek, D Elcik, S Karadavut, V Simsek, M Tulmac, Özcan Örsçelik, B Calapkorur, Ali E...

2013 Hakemli SCI 30 atıf Link
A Link between the Intrarenal Renin Angiotensin System and Hypertension in Autosomal Dominant Polycystic Kidney Disease

American Journal of Nephrology, vol. 38, no. 3, pp. 218–225

Ismail Kocyigit, Mahmut Ilker Yilmaz, Aydin Unal, Fahir Ozturk, Eray Eroglu, Cevat Yazici, Özcan Örs...

2013 Hakemli SCI 34 atıf Link
Mean Platelet Volume and Its Relation With Arterial Stiffness in Patients With Normotensive Polycystic Kidney Disease

Journal of Investigative Medicine, vol. 61, no. 3, pp. 597–603

Özcan Örsçelik, İsmail Koçyiğit, Mahmut Akpek, Orhan Doğdu, Coşkun Kaya, Aydın Ünal, Murat Hayri Sip...

2013 Hakemli SCI 7 atıf Link
Acute Effects of Intracoronary Nitroglycerin and Diltiazem in Coronary Slow Flow Phenomenon

Journal of Investigative Medicine, vol. 61, no. 1, pp. 45–49

İbrahim Özdoğru, Cemil Zencir, Ali Doğan, Özcan Örsçelik, Mehmet Tuğrul İnanç, Ahmet Çelik, Mustafa ...

2013 Hakemli SCI 14 atıf Link
Improved arterial stiffness in mitral stenosis after successful percutaneous balloon valvuloplasty

Cardiology journal, vol. 19, no. 6, pp. 586–590

Ozdogru Ibrahim, Celik Ahmet, Dogan Ali, Orscelik Ozcan, Sahin Omer, Elcik Deniz, Saka Tolga, Topsak...

2012 Hakemli SCI-Expanded 3 atıf Link
High Levels of Serum Uric Acid Predict Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome

Angiology, vol. 63, no. 6, pp. 448–452

Mustafa Duran, Nihat Kalay, Mahmut Akpek, Özcan Örsçelik, D Elcik, A Ocak, Mehmet Tuğrul İnanç, H A ...

2012 Hakemli SCI 35 atıf Link
Early Arterial Stiffness and Inflammatory Bio-Markers in Normotensive Polycystic Kidney Disease Patients

American Journal of Nephrology, vol. 36, no. 1, pp. 11–18

İsmail Koçyiğit, Mehmet Güngör Kaya, Özcan Örsçelik, Coşkun Kaya, Mahmut Akpek, Halit Zengin, Murat ...

2012 Hakemli SCI 39 atıf Link
Circumflex Coronary Artery Originating From The Pulmonary Artery Bifurcation

Journal of Contemporary Medicine, vol. 2, no. 2, pp. 135–135

Özcan Örsçelik, Ali Doğan, Orhan Doğdu, Ahmet Çelik

2012 Hakemli DOAJ, openAIRE, CrossRef, Scilit, GoogleScholar
Impairment of heart rate recovery index in autosomal-dominant polycystic kidney disease patients without hypertension

Blood Pressure, vol. 21, no. 5, pp. 300–305

Özcan Örsçelik, İsmail Koçyiğit, Oguzhan Baran, Coskun Kaya, Orhan Doğdu, Halit Zengin, Serhat Karad...

2012 Hakemli SCI 8 atıf Link
Frequency of contrast-induced nephropathy in patients with a history of coronary angiography and SGLT-2 inhibitor use

, vol. , no. , pp. 1–229

Cuma Yeşildaş, Muhammed Adıyaman, Emrah Yeşil, Ahmet Çelik, İsmail Türkay Özcan, Özcan Örsçelik

2023 Link
The relationship between urinary angiotensinogen and mortality in heart failure patients with reduced ejection fraction

, vol. 26, no. Supp1, pp. S1–S177

Tarık Kıvrak, Emrah Yeşil, Ali Orçun Sürmeli, Hakan Uyar, Burcu Yağmur, Özcan Örsçelik, Buğra Özkan,...

2022 Link
Trombüs aspirasyonuna sekonder gelişen bir komplikasyon: Yaygınsol sistem trombüsü ve başarılı yönetimi

Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 12, no. 12, pp. 150–155

Özcan Örsçelik, Mert Koray Özcan, Ali Orçun Sürmeli, Buğra Özkan, İsmail Türkay Özcan, Ahmet Çelik, ...

2019 Hakemli TR DİZİN
Kalp Yetersizliği ile Takip Edilen Hastalarda Anemi Sıklığı : Pilot Çalışma

Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, vol. 8, no. 3, pp. 212–217

Özcan Örsçelik, Buğra Özkan

2018 Hakemli TR DİZİN Link
Ksantelazma ile Başvuran Homozigot Familyal Hiperkolesterolemi Olgusu

Causapedia, vol. 7, no. 2, pp. 73–75

Özcan Örsçelik, Emre Ertan Şahin, Ahmet Çelik

2018 Hakemli TR DİZİN
Ailevi hiperkolesterolemi hastalarında lipid aferezin lipid profili ve hs-CRP üzerine etkileri

Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 11, no. 1, pp. 24–31

Fatma Köksal, Buğra Özkan, Özcan Örsçelik, Selçuk Ayhan, Emrah Yeşil, Ahmet Çelik, İsmail Türkay Özc...

2018 Hakemli TR DİZİN Link
Stabil angina pektoris ile başvuran hastalarda ciddi kroner arter darlığı ile fragmente QRS arasındaki ilişkinin araştırılması

Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 11, no. 2, pp. 167–173

Buğra Özkan, Özcan Örsçelik, Ayça Arslan, Emre Ertan Şahin, İsmail Türkay Özcan

2018 Hakemli TR DİZİN Link
Diffuse Alveolar Hemorrhage Due to Severe Aortic ValveStenosis

TIP ARAŞTIRMALARI ARŞİVİ, vol. 2, no. 1, pp. 14–16

Özcan Örsçelik, Buğra Özkan, Ayça Arslan, Kadir Burak Akgün, Eylem Sercan Özgür, Cengiz Özge, İsmail...

2017 Hakemli Endekste taranmıyor
Günlük pratikte kullanılan topikal oftalmik timolol’e bağlı gelişen ciddi bradikardi: Vaka örneği

Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 10, no. 2, pp. 156–157

Özcan Örsçelik, Buğra Özkan, Emre Ertan Şahin, Ali Orçun Sürmeli, İsmail Türkay Özcan

2017 Hakemli TR DİZİN Link
The Relationship Between Osteoprotegerin/RANKL Axis and Arterial Stiffness in Osteopenic/Osteoporotic Renal Transplantation Recipients

Turkish Nephrology Dialysis Transplantation, vol. 24, no. 2, pp. 181–188

İsmail Koçyiğit, Kültigin Türkmen, Ender Doğan, Özkan Güngör, Özcan Örsçelik, Çiğdem Karakukcu, Eray...

2015 Hakemli TR DİZİN Link
Appropriateness of aspirin use among diabetic patients in primary prevention of atherosclerotic cardiovascular diseases: an analysis of the ASSOS study

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol. 27, no. 1, pp. 307–314

Demirci E., Celik O., Cil C., Tanik V. O., Sancar K. Memic, Orscelik O., Resulzade M. M., Kaya C., K...

2023 1 atıf Link
Effect of altitude on ticagrelor-induced dyspnea in patients with acute coronary syndrome

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol. 51, no. 4, pp. 030006052110659–

Kocabay Gonenc, Kivrak Tarik, Karaca Ozkan, Karasu Mehdi, Kaya Hakki, Kanar Batur, Orscelik Ozcan, K...

2023 Link
Okskarbazepine Bağlı Gelişen Değişken Tip AV Blok

Türk Nöroloji Dergisi, vol. , no. , pp. 281–282

Özcan Örsçelik, Buğra Özkan, Ertan Emre Şahin, Ozan Sakarya, Ahmet Çelik, Mehmet Necdet Akkuş, İsmai...

2018