Investigation of RhoA, ROCK1, and ROCK2 Gene Expressions in Autism Spectrum Disorders
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Emine Merve Kalınlı, Etem Akbaş, Duygu Yolal Ertural, Serkan Güneş, Kansu Büyükafşar
Comparison of bone marrow stem cells and cell-derived exosomes on oleic acidinduced lung injury in rats
Hıppokratıa Medıcal Journal, vol. 28, no. 3, pp. 100–108
Elif Önsöz, Gamze Ayar, Hadra Şafak Üstük, Leyla Bahar, Badel İnce, Mehmet Oğuz Köksel, Erkan Maytal...
Investigation of the anticancer effect of newly synthesized palladium conjugate Schiff base metal complexes on non-small cell lung cancer cell line and mouse embryonic fibroblast cell line
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Burcu Demirbağ, Kansu Büyükafşar, Hamide Kaya, Metin Yıldırım, Öznur Bucak, Hakan Ünver, Semra Erdoğ...
The effect of testosterone replacement therapy on bladder functions, histology, apoptosis, and Rho-kinase expression in bladder outlet obstruction and hypogonadism rat model
TURKISH JOURNAL OF MEDICAL SCIENCES, vol. 51, no. 3, pp. 1491–1499
Barış Saylam, Ozan Efesoy, Rabia Bozdoğan Arpacı, Rukiye Nalan Tiftik, Mesut Tek, Kansu Büyükafşar, ...
RhoA, ROCK-1, and ROCK-2 Gene Expression and Polymorphisms in Cholesteatoma Patients
JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY, vol. 17, no. 6, pp. 530–535
Kansu Büyükafşar, Kemal Görür, Cengiz Özcan, Etem Akbaş, Onur İsmi, Duygu Yolal Ertural, Ayşegül Çet...
Effects of the Rho/Rho-Kinase Pathway on Perfusion Pressure in the Isolated-Perfused Rat Hind Limb Vascular Bed
BALKAN MEDICAL JOURNAL, vol. 38, no. 5, pp. 304–309
Esra İlhan, Esra Yıldız, Kansu Büyükafşar, Rukiye Nalan Tiftik, Mehmet Ata Seçilmiş, M Ata Seçilmiş,...
Pharmacology of Botulinum Toxins: From Poison to Remedy
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Kansu Büyükafşar
Role of the Rho/Rho-kinase Pathway in Endometrial Adenocarcinoma Cell Proliferation
UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, vol. 29, no. 4, pp. 219–226
Rukiye Nalan Tiftik, İsmail Ün, Derya Yetkin, Kansu Büyükafşar
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle
LIFE SCIENCES, vol. 198, no. , pp. 46–55
Leyla Sahin, Leyla Şahin, Özge Selin Çevik, Dilan Deniz Koyuncu, Dilan Deniz Yılmaz, Kansu Büyükafşa...
Suppressive effect of Rho-kinase inhibitors Y-27632 and fasudil on spike-and-wave discharges in genetic absence epilepsy rats from Strasbourg (GAERS)
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Nihan Çarçak Yılmaz, Yavuz Melis, Tuğba Karamahmutoğlu, Akif Hakan Kurt, Meral Urhan Küçük, Filiz On...
The Role of Rho/Rho-Kinase Pathway in the Pathogenesis of Cholesteatoma
Otology Neurotology, vol. 38, no. 4, pp. 516–520
Murat Yeşilova, Mesut Yeşilova, Kemal Görür, Onur İsmi, Cengiz Özcan, Kansu Büyükafşar
Rho/rho-kinase signalling in chronically alcohol-fed mice
TURKISH JOURNAL OF MEDICAL SCIENCES, vol. 47, no. 2, pp. 668–674
Havva Kubat, Ahmet Sencer Yurtsever, Kansu Büyükafşar
Sağlık bilimleri alanında bilimsel makale yazma teknikleri
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Kansu Büyükafşar
Comparative investigation of antitumoral effectiveness of Rho-kinase inhibitor Y-27632, pravastatin and atorvastatin in anaplastic thyroid cancer cell culture
Journal of Oncological Sciences, vol. 3, no. 2, pp. 62–65
Erdinç Nayır, Selver Çor, Selver Cor, Zuhal Altıntaş, Zuhal Mert Altintas, Zuhal Mert Altıntaş, Kans...
The protective role of G protein coupled estrogen receptor1 GPER 1 on methotrexate ınduced nephrotoxicity in human renal epithelium cells
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Combining Epinephrine and Esmolol Attenuates Excessive Autophagy and Mitophagy in Rat Cardiomyocytes Following Cardiac Arrest
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Investigation of Rho kinase expressions and polymorphisms in mantle cell lymphoma patients
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Effects of 17β-estradiol and progesterone on the production of adipokines in differentiating 3T3-L1 adipocytes: Role of Rho-kinase
CYTOKINE, vol. 72, no. 2, pp. 130–134
Mehtap Pektaş, Akif Hakan Kurt, İsmail Ün, Rukiye Nalan Tiftik, Kansu Büyükafşar
Effects of ethanol withdrawal on the activity of rho-kinase in rat brain
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol. 116, no. 08, pp. 490–493
Akif Hakan Kurt, Enis Macit, İsmail Tayfun Uzbay, Kansu Büyükafşar, Vefa Ahsen, Ayşe Gül Gürek, Burc...
Rho-kinase Levels in Testicular Ischemia-reperfusion Injury and Effects of Its Inhibitor, Y-27632, on Oxidative Stress, Spermatogenesis, and Apoptosis
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Selahittin Çayan, Ünal Nil Doğruer, B Sağlam, Barış Saylam, Saylam Barış, Nil D Ünal, Eyüp Naci Tift...
The production of vasoconstriction-induced residual NO modulates perfusion pressure in rat mesenteric vascular bed
PERFUSION-UK, vol. 29, no. 6, pp. 488–495
Mehmet Ata Seçilmiş, Özlem Yorulmaz Özü, Olcay Ergünhan Kıroğlu, Ergin Şingirik, Kansu Büyükafşar
The Functional Significance of the Rho/Rho-Kinase Pathway in Human Erythrocytes
TURKISH JOURNAL OF HEMATOLOGY, vol. 31, no. 2, pp. 168–174
Rukiye Nalan Tiftik, Oğuz Kerim Başkurt, Seval Kul, Kansu Büyükafşar
Effect of ornithine on the ileal histology nitric oxide production and lipid peroxidation in LPS induced endotoxemia
ACTA MEDICA OKAYAMA, vol. 57, no. 3, pp. 117–122
Mustafa Musa Dirlik, Kansu Büyükafşar, İsmail Hakkı Cinel, Zeliha Leyla Cinel, Mehmet Çağlıkülekçi, ...
Alfacalcidol suppresses α-receptor-mediated vasoconstriction via an endothelium dependent mechanism
TURKISH JOURNAL OF MEDICAL SCIENCES, vol. 43, no. 2, pp. 238–244
İsmail Ün, Akif Hakan Kurt, Ali Batuş, Kansu Büyükafşar
G protein coupled estrogen receptor1 GPER1 may mediate Rho kinase ROCK 2 up regulation in coronary endothelial cells
Endocrine Regulations, vol. 47, no. 02, pp. 75–84
Akif Hakan Kurt, Rukiye Nalan Tiftik, İsmail Ün, Sibel Göksel, Sibel Ülker, Kansu Büyükafşar
Vasoconstriction induced by G1, a G-protein-coupled oestrogen receptor1 (GPER-1) agonist, in the isolated perfused rat kidney
EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 702, no. 1-3, pp. 71–78
Akif Hakan Kurt, Kansu Büyükafşar
Hyperosmolar glucose induces vasoconstriction through Rho/Rho-kinase pathway in the rat aorta
FUNDAMENTAL & CLINICAL PHARMACOLOGY, vol. 27, no. 3, pp. 244–251
İsmail Ün, Akif Hakan Kurt, Kansu Büyükafşar
AUGMENTATION OF THE CYTOTOXICITY OF IBANDRONATE BY Y-27632 IN PROSTATE CANCER CELL LINES
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Alper Ata, Ahmet Ata Özçimen, Akif Hakan Kurt, Rukiye Nalan Tiftik, Ali Arıcan, Kansu Büyükafşar
THE EFFECT OF TESTOSTERONE TREATMENT ON BLADDER FUNCTIONS HISTOLOGY APOPTOSIS AND RHO KINASE EXPRESSION IN BLADDER OUTLET OBSTRUCTION AND HYPOGONADISM RAT MODEL
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Barış Saylam, Ozan Efesoy, Rabia Bozdoğan Arpacı, Rukiye Nalan Tiftik, Mesut Tek, Kansu Büyükafşar, ...
CDP choline induced contractions in the mouse gastric fundus through purinoceptors and Rho Rho kinase signalling
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Güldalı Özge, Vahide Savcı, Kansu Büyükafşar
Proton pump inhibitors omeprazole lansoprazole and pantoprazole induce relaxation in the rat lower oesophageal sphincter
Journal of Pharmacy and Pharmacology, vol. 63, no. 10, pp. 1295–1300
İsmail Ün, Ahmet Sencer Yurtsever, A Sencer Yurtsever, Mehtap Pektaş, Mehtap Pektas, Aydın Erenmemi...
Antiepileptic effects of two Rho kinase inhibitors Y 27632 and fasudil in mice
British Journal of Pharmacology, vol. 155, no. 1, pp. 44–51
Salim Yalçın İnan, Kansu Büyükafşar
Nitric Oxide Does Not Downregulate Rho Kinase ROCK 2 Expression in Rat Coronary Endothelial Cells
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Rukiye Nalan Tiftik, Ayşe Erol, Gülcihan Mehtap Köksal, Mehtap Çınar, Havva Kubat, Kubat Havva, Must...
Nebivolol but Not Metoprolol Improves Endothelial Function of the Corpus Cavernosum in Apolipoprotein E Knockout Mice
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 325, no. 3, pp. 818–823
Arıkan Onur, Kansu Büyükafşar
Urocortin Induces Endothelium Dependent Vasodilatation and Hyperpolarization of Rat Mesenteric Arteries by Activating Ca2 Activated K Channels
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, vol. 213, no. 1, pp. 89–98
Mehmet Ata Secilmiş, Özlem Yorulmaz Özü, Mustafa Emre, Kansu Büyükafşar, Olcay Kıroglu Ergurhan, Fat...
Role of Rho kinase in contractions of ureters from rabbits with unilateral ureteric obstruction
BJU International, vol. 100, no. 5, pp. 1166–1171
Burak Turna, Mehtap G Çınar, Gülcihan Mehtap Çınar, Abdullah Erdem Canda, Elif C Orhan, Mehmet Bülen...
Association of Angiotensin Converting Enzyme Gene Insertion Deletion Polymorphism with Allergic Contact Dermatitis
Basic & Clinical Pharmacology & Toxicology, vol. 101, no. 2, pp. 101–103
Muradiye Nacak, Zulal Erbagci, Zülal Erbağcı, Kansu Büyükafşar, Ahmet Sencer Yurtsever, Sencer Yurts...
Rho kinase inhibitor Y 27632 has an antinociceptive effect in mice
European Journal of Pharmacology, vol. 541, no. 1-2, pp. 49–52
Yalçın İl, Kansu Büyükafşar, İpek Yalçın, Akif Hakan Kurt, Rukiye Nalan Tiftik, Seyhan Şahan Fırat, ...
Contribution of Rho kinase in human gallbladder contractions
European Journal of Pharmacology, vol. 540, no. 1-3, pp. 162–167
Kansu Büyükafşar, Tamer Akça, Rukiye Nalan Tiftik, Seyhan Şahan Fırat, Süha Aydın
Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli
European Journal of Pharmacology, vol. 528, no. 1-3, pp. 169–175
Seyhan Şahan Fırat, Rukiye Nalan Tiftik, Muradiye Nacak, Kansu Büyükafşar
Protective Effect of iL/i-Arginine Intake on the Impaired Renal Vascular Responses in the Gentamicin-Treated Rats
Nephron Physiology, vol. 100, no. 2, pp. p13–p20
M Ata Seçilmiş, Mehmet Ata Seçilmiş, Yusuf Karataş, Özlem Yorulmaz, Özlem Özü, Kansu Büyükafşar, Erg...
Rho kinase ROCK 1 and ROCK 2 upregulation in oleic acid induced lung injury and its restoration by Y 27632
European Journal of Pharmacology, vol. 510, no. 1-2, pp. 135–142
Mehmet Oğuz Köksel, Çağlar Yıldırım, C Yıldırım, Rukiye Nalan Tiftik, Havva Kubat, H Kubat, Lülüfer ...
The urinary 5 hydroxyindole acetic acid and plasma nitric oxide levels in irritable bowel syndrome a preliminary study
Scottish medical journal, vol. 50, no. 50(1), pp. 27–9
Aziz Yazar, Kansu Büyükafşar, Gürbüz Polat, Cengiz Pata, Emine Arzu Kanık, Eyüp Naci Tiftik, Özlen T...
Rho kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed
European Journal of Pharmacology, vol. 485, no. 1-3, pp. 263–268
Kansu Büyükafşar, Arıkan Onur, Onur Arikan, Onur Arıkan, Mustafa Ark, Mehmet Ata Seçilmiş, İsmail Ün...
Expression of Rho kinase ROCK 1 and ROCK 2 and its substantial role in the contractile activity of the sheep ureter
BRITISH JOURNAL OF PHARMACOLOGY, vol. 143, no. 3, pp. 431–437
Adnan Levent, Kansu Büyükafşar
Effects of HA 1077 and Y 27632 Two Rho Kinase Inhibitors in the Human Umbilical Artery
CELL BIOCHEMISTRY AND BIOPHYSICS, vol. 41, no. 3, pp. 331–342
Mustafa Ark, Elif Özveren, Faik Gürkan Yazıcı, Belma Korkmaz, Kansu Büyükafşar, Onur Arıkan, Havva K...
Effect of tempol 4 hydroxy tempo on gentamicin induced nephrotoxicity in rats
FUNDAMENTAL & CLINICAL PHARMACOLOGY, vol. 18, no. 1, pp. 79–83
Yusuf Karataş, Mehmet Ata Seçilmiş, İbrahim Karayaylalı, Figen Doran, Kansu Büyükafşar, Ergin Şingir...
Upregulation of Rho kinase ROCK 2 expression and enhanced contraction to endothelin 1 in the mesenteric artery from lipopolysaccharide treated rats
EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 498, no. 1-3, pp. 211–217
Kansu Büyükafşar, Onur Arıkan, Mustafa Ark, Havva Kubat, Elif Özveren
Expression of Rho kinase and its functional role in the contractile activity of the mouse vas deferens
BRITISH JOURNAL OF PHARMACOLOGY, vol. 140, no. 4, pp. 743–749
Kansu Büyükafşar, Mustafa Ark, Adnan Levent
Mediation of nitric oxide from photosensitive stores in the photorelaxation of the rabbit corpus cavernosum
European Journal of Pharmacology, vol. 459, no. 2-3, pp. 263–267
Kansu Büyükafşar, Adnan Levent, İsmail Ün, Mustafa Ark, Arıkan Onur, Özveren Elif
Therapeutic plasma exchange for multidrug intoxication A case report
Journal of Clinical Apheresis, vol. 18, no. 3, pp. 132–133
Eyüp Naci Tiftik, Ahmet Alper Kıykım, Engin Altıntaş, Kerem Sezer, Nurcan Doruk, Orhan Sezgin, Seyer...
Effect of ornithine on the ileal histology nitric oxide production andlipid peroxidation in LPS induced endotoxemia
ACTA MEDICA OKAYAMA, vol. 57, no. 3, pp. 117–122
Mustafa Musa Dirlik, Kansu Büyükafşar, İsmail Hakkı Cinel, Zeliha Leyla Cinel, M Çağlıkülekçi, Lülüf...
Effects of the Rho kinase inhibitors Y 27632 and fasudil on the corpus cavernosum from diabetic mice
European Journal of Pharmacology, vol. 472, no. 3, pp. 235–238
Kansu Büyükafşar, İsmail Ün, Adnan Levent, Mustafa Ark, Arıkan Onur, Özveren Elif
Involvement of Rho Rho kinase signalling in the contractile activity and acetylcholine release in the mouse gastric fundus
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 303, no. 3, pp. 777–781
Kansu Büyükafşar, Adnan Levent
Effects of glibenclamide metformin and insulin on the incidence and latency of death by oubain induced arrhythmias in mice
Pharmacological Research, vol. 45, no. 3, pp. 183–187
Aziz Yazar, Gürbüz Polat, İsmail Ün, Levent Adnan, Adnan Levent, Ayşe Kaygusuz, Aa Kaygusuz, Kaygusu...
THE ROLE OF POLY ADP RIBOSE SYNTHETASE INHIBITION IN PREVENTING ENDOTOXEMIA INDUCED INTESTINAL EPITHELIAL APOPTOSIS
Pharmacological Research, vol. 46, no. 2, pp. 119–127
İsmail Hakkı Cinel, Kansu Büyükafşar, Zeliha Leyla Cinel, Şebnem Atıcı, A Polat, Ayşe Polat, Lülüfer...
Simultaneous determination of codeine and ethyl morphine HCL in tablet formulations using LC
Journal of Pharmaceutical and Biomedical Analysis, vol. 26, no. 1, pp. 15–21
Kansu Büyükafşar
Formation of nitric oxide from nitroxyl anion role of quinones and ferricytochrome c
BRITISH JOURNAL OF PHARMACOLOGY, vol. 132, no. 1, pp. 165–172
Kansu Büyükafşar, Wıllıam Martın
Effect of trapidil an antiplatelet and vasodilator agent on gentamicin induced nephrotoxicity in rats
Pharmacological Research, vol. 44, no. 4, pp. 321–328
Kansu Büyükafşar, Büyükavşar Kansu, Aziz Yazar, Duygu Düşmez Apa, A Yazar, D Düşmez, Ahmet Hakan Özt...
Effects of some divalent cations on nitrergic relaxations in the mouse corpus cavernosum
Wiley, vol. 15, no. 5, pp. 343–348
Fatma Peyman Ertuğ, Kansu Büyükafşar, Eda Kumcu, Cemil Göçmen, Mehmet Ata Seçilmiş, Erğin Şingirik, ...
Oxidation of nitroxyl anion to nitric oxide by copper ions
BRITISH JOURNAL OF PHARMACOLOGY, vol. 131, no. 2, pp. 356–362
Sılvıa Nellı, Mark Hıllen, Kansu Büyükafşar, Wıllıam Martın
Depletion and restoration of the putative photosensitive materials store yielding nitric oxide in the isolated mouse gastric fundus
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 290, no. 2, pp. 768–773
Kansu Büyükafşar, Emine Demirel Yılmaz, Cemil Göçmen, Atila Dikmen
The Role of Steroid Receptors in the Proliferation and Migration of Endometrial Adenocarcinoma HEC1A Cell Line
Dicle Tıp Dergisi, vol. 50, no. 3, pp. 327–334
Khairat Al Hennawi, Rukiye Nalan Tiftik, İsmail Ün, Kansu Büyükafşar
Bakteriyel lipopolisakkaridin preadiposit diferensiyasyonu üzerine etkisi: NO’nun ve Rho-kinaz enziminin olası katkısı
Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 12, no. 2, pp. 257–270
Ahmet Sencer Yurtsever, Kansu Büyükafşar
Effects of GPER-1 receptor activation on the reactivity of pulmonary vascular bed and its possible protective role on ischemia/reperfusion
JOURNAL OF RESEARCH IN PHARMACY, vol. 22, no. 1, pp. 95–101
Gökçen Telli, Banu Cahide Tel, Kansu Büyükafşar, Bülent Gümüşel
The Role of Rho/Rho-Kinase Pathway in the Pathophysiology of Absence Epilepsy
EPILEPSI, vol. 25, no. 1, pp. 1–7
Nihan Çarçak Yılmaz, Yavuz Melis, Melis Yavuz, Tuğba Karamahmutoğlu, Tuğba Eryiğit, Akif Hakan Kurt,...
Sıçan Koroner Mikrovasküler Endotel Hücre Kültüründe Östrojenin Oluşturduğu RhoA Up regülasyonu Üzerine ICI182 780 Progesteron ve Testosteronun Etkisi
Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 4, no. 2, pp. 17–21
Akif Hakan Kurt, Rukiye Nalan Tiftik, İsmail Ün, Sibel Göksel, Kansu Büyükafşar
Preadipositlerde 3T3 L1 Östrojenin Adiposit Diferansiyasyonu Üzerine Olası Etkisi Rho Rho kinaz Yolağının Olası Katkısı
Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 4, no. 2, pp. 22–28
Mehtap Pektaş, Akif Hakan Kurt, Rukiye Nalan Tiftik, İsmail Ün, Kansu Büyükafşar
Kronik Myeloid Lösemi K 562 hücre hattında siklofosfamidin apoptoza etkileri
Mersin Üniversitesi Sağlık Bilimleri Dergisi, vol. 1, no. 2, pp. 12–18
Ebru Derici Eker, Nurcan Aras, Kansu Büyükafşar, Rukiye Nalan Tiftik
Sıçan torasik aorta praparatında çeşitli ajanlar tarafından oluşturulan kontraktil aktivite üzerinde amilorid ve vanadat etkileri ile ilgili bir çalışma
Çukurova Üniversitesi Sağlık Bilimleri Dergisi, vol. 12, no. 1-2-3, pp. 11–19
Eda Karabal Kumcu, Atçı Şerare, Işıl Öcal, Cemil Göçmen, Yusuf Karataş, Fatma Peyman Ertuğ, Kansu Bü...
İnsan Eritrositlerinde Rho/Rho-Kinaz Yolağının Fonksiyonel Önemi
Turkish Journal of Hematology, vol. 31, no. 2, pp. 168–174
R. Nalan Tiftik, Oğuz K. Başkurt, Seval Kul, Kansu Buyukafsar
Peritonit oluşturulan sıçanlarda high mobility group box-1 ve tümör nekroz faktör-alfa inhibisyonunun barsak morfolojisi ve motilite üzerine etkisi
Çocuk Cerrahisi Dergisi, vol. 22, no. 1, pp. 15–24
Tuştaş Burçin Ay, Dinçer Avlan, Ayşe Polat, Lülüfer Tamer, Kansu Buyukafsar, Selim Aksöyek
The effect of L-Ornithine on the inner ear of rats in the lipopolysaccharide induced endotoxemia model
KBB-Forum, vol. 1, no. 2, pp. 36–40
Kemal Görür, Cengiz Özcan, Leyla Cinel, Kansu Buyukafsar, Lülüfer Tamer, Ismail Cinel